{"id":7243,"date":"2026-08-23T00:15:45","date_gmt":"2026-08-22T22:15:45","guid":{"rendered":"https:\/\/www.siboakademia.com\/?p=7243"},"modified":"2026-09-02T13:18:23","modified_gmt":"2026-09-02T11:18:23","slug":"sibo-histaminova-intolerancia","status":"publish","type":"post","link":"https:\/\/www.siboakademia.com\/cz\/sibo-histaminova-intolerancia\/","title":{"rendered":"Histam\u00ednov\u00e1 intolerancia a SIBO: Ak\u00e1 je medzi nimi s\u00favislos\u0165?"},"content":{"rendered":"
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Histam\u00ednov\u00e1 intolerancia a SIBO: Ak\u00e1 je medzi nimi s\u00favislos\u0165?<\/h1>

\"Ak\u00e1
Tr\u00e1viace probl\u00e9my, ako s\u00fa nafukovanie, bolesti brucha, hna\u010dka, reflux \u010di nepr\u00edjemn\u00e9 reakcie po jedle, nemusia ma\u0165 v\u017edy iba jednu pr\u00ed\u010dinu. Mnoh\u00e9 z t\u00fdchto pr\u00edznakov sa toti\u017e objavuj\u00fa pri r\u00f4znych tr\u00e1viacich probl\u00e9moch a m\u00f4\u017eu sa navz\u00e1jom prekr\u00fdva\u0165.<\/p>

Ak sa n\u00e1m podar\u00ed odhali\u0165 jednu mo\u017en\u00fa pr\u00ed\u010dinu, neznamen\u00e1 to automaticky, \u017ee sa tam cesta kon\u010d\u00ed a \u017ee pr\u00e1ve ona vysvet\u013euje v\u0161etky na\u0161e \u0165a\u017ekosti.<\/p>

\u010casto sa toti\u017e st\u00e1va, \u017ee ak m\u00e1 \u010dlovek napr\u00edklad potvrden\u00e9 SIBO, s\u00fastred\u00ed sa u\u017e iba na SIBO. A tak \u010fal\u0161\u00ed probl\u00e9m, ktor\u00fd tam m\u00f4\u017ee by\u0165 s\u00fa\u010dasne, m\u00f4\u017ee zosta\u0165 nepov\u0161imnut\u00fd.<\/p>

Ak sa so SIBO stret\u00e1vate prv\u00fdkr\u00e1t a chcete sa o \u0148om dozvedie\u0165 viac, v\u0161etko podstatn\u00e9 som zhrnula v bezplatnej e-knihe o SIBO, ktor\u00fa si m\u00f4\u017eete stiahnu\u0165 \u2192tu<\/strong><\/a>.<\/span><\/p>

Podobne je to aj pri in\u00fdch probl\u00e9moch. Ak m\u00e1 niekto napr\u00edklad diagnostikovan\u00fa histam\u00ednov\u00fa intoleranciu, je ve\u013emi \u013eahk\u00e9 prip\u00edsa\u0165 v\u0161etky \u0165a\u017ekosti pr\u00e1ve histam\u00ednu. Len\u017ee za \u010das\u0165ou pr\u00edznakov sa m\u00f4\u017ee skr\u00fdva\u0165 e\u0161te nie\u010do \u010fal\u0161ie.<\/p>

A pr\u00e1ve SIBO a probl\u00e9my s histam\u00ednom id\u00fa \u010dastokr\u00e1t ruka v ruke. Ke\u010f\u017ee maj\u00fa ve\u013ea podobn\u00fdch pr\u00edznakov, nemus\u00ed by\u0165 v\u017edy jednoduch\u00e9 odhali\u0165, \u010do v\u0161etko sa za na\u0161imi probl\u00e9mami skr\u00fdva.<\/p>

Ak v\u00e1s teda dlhodobo tr\u00e1pi napr\u00edklad nafukovanie alebo in\u00e9 tr\u00e1viace probl\u00e9my a prid\u00e1vaj\u00fa sa k tomu aj \u010fal\u0161ie pr\u00edznaky mimo tr\u00e1venia, stoj\u00ed za to zamyslie\u0165 sa, \u010di za t\u00fdm nem\u00f4\u017ee by\u0165 aj histam\u00edn.<\/p>

Mo\u017eno je to pr\u00e1ve \u010fal\u0161\u00ed k\u00fasok sklada\u010dky, ktor\u00fd v\u00e1m doteraz ch\u00fdbal.<\/p>

Po\u010fme si preto najsk\u00f4r vysvetli\u0165, \u010do histam\u00edn vlastne je, \u010do sa deje, ke\u010f ho na\u0161e telo nedok\u00e1\u017ee spr\u00e1vne odb\u00farava\u0165, a \u010do s t\u00fdm v\u0161etk\u00fdm m\u00e1 spolo\u010dn\u00e9 na\u0161e \u010drevo.<\/p>

\u010co je histam\u00edn?<\/strong><\/h2>

Histam\u00edn je prirodzen\u00e1 l\u00e1tka, ktor\u00e1 sa nach\u00e1dza v na\u0161om tele a m\u00e1 v \u0148om mno\u017estvo d\u00f4le\u017eit\u00fdch \u00faloh. Podie\u013ea sa napr\u00edklad na imunitn\u00fdch reakci\u00e1ch, tvorbe \u017eal\u00fado\u010dnej kyseliny a funguje aj ako sign\u00e1lna l\u00e1tka v nervovom syst\u00e9me. \u010cas\u0165 histam\u00ednu si vytv\u00e1ra na\u0161e telo a \u010fal\u0161iu \u010das\u0165 prij\u00edmame prostredn\u00edctvom potravy.<\/p>

Za norm\u00e1lnych okolnost\u00ed si na\u0161e telo dok\u00e1\u017ee s histam\u00ednom bez probl\u00e9mov poradi\u0165. Mno\u017estvo histam\u00ednu, ktor\u00e9 prijmeme alebo si ho telo vytvor\u00ed, je v rovnov\u00e1he s mno\u017estvom, ktor\u00e9 dok\u00e1\u017eeme odb\u00fara\u0165. Pokia\u013e t\u00e1to rovnov\u00e1ha funguje, histam\u00edn n\u00e1m nesp\u00f4sobuje probl\u00e9my.<\/p>

Probl\u00e9m nast\u00e1va a\u017e vtedy, ke\u010f sa t\u00e1to rovnov\u00e1ha naru\u0161\u00ed. Histam\u00ednu m\u00f4\u017ee by\u0165 zrazu viac, ako ho na\u0161e telo dok\u00e1\u017ee priebe\u017ene odb\u00farava\u0165. Za\u010dne sa v organizme hromadi\u0165 a pr\u00e1ve vtedy sa m\u00f4\u017eu objavi\u0165 r\u00f4zne nepr\u00edjemn\u00e9 pr\u00edznaky.<\/p>

Pri odb\u00faravan\u00ed histam\u00ednu prijat\u00e9ho potravou zohr\u00e1va d\u00f4le\u017eit\u00fa \u00falohu enz\u00fdm diaminooxid\u00e1za (DAO)<\/strong>, ktor\u00fd sa nach\u00e1dza vo ve\u013ekej miere pr\u00e1ve v sliznici tenk\u00e9ho \u010dreva. Ak je jeho aktivita zn\u00ed\u017een\u00e1, histam\u00edn prijat\u00fd potravou sa nemus\u00ed dostato\u010dne odb\u00farava\u0165 a m\u00f4\u017ee sa za\u010da\u0165 v organizme hromadi\u0165.<\/p>

A ako vlastne spozna\u0165, \u017ee za na\u0161imi probl\u00e9mami m\u00f4\u017ee by\u0165 pr\u00e1ve histam\u00edn?<\/p>

Ako sa histam\u00ednov\u00e1 intolerancia diagnostikuje?<\/strong><\/h2>

Diagnostika histam\u00ednovej intolerancie nie je \u00faplne jednoduch\u00e1 a ned\u00e1 sa spo\u013eahlivo potvrdi\u0165 iba jedn\u00fdm odberom krvi. \u010casto sa vy\u0161etruje hladina alebo aktivita enz\u00fdmu DAO v krvi. Samotn\u00fd v\u00fdsledok v\u0161ak nemus\u00ed da\u0165 jednozna\u010dn\u00fa odpove\u010f. U niektor\u00fdch \u013eud\u00ed m\u00f4\u017ee by\u0165 DAO zn\u00ed\u017een\u00e9, no histam\u00ednov\u00fa intoleranciu nemaj\u00fa. Naopak, u in\u00fdch m\u00f4\u017ee by\u0165 hodnota DAO v norme, hoci histam\u00ednov\u00fa intoleranciu maj\u00fa.<\/p>

Hodnota DAO nameran\u00e1 v krvi toti\u017e nemus\u00ed presne odzrkad\u013eova\u0165, ako dobre sa histam\u00edn odb\u00farava priamo v \u010dreve. Preto je chybou posudzova\u0165 histam\u00ednov\u00fa intoleranciu iba na z\u00e1klade jedn\u00e9ho laborat\u00f3rneho v\u00fdsledku z krvi, ako sa to v praxi \u010dastokr\u00e1t rob\u00ed.<\/p>

Pri diagnostike je potrebn\u00e9 posklada\u0165 viacero inform\u00e1ci\u00ed dohromady. D\u00f4le\u017eit\u00e9 s\u00fa pr\u00edznaky a ich s\u00favislos\u0165 s konkr\u00e9tnymi potravinami, v\u00fdsledky \u010fal\u0161\u00edch vy\u0161etren\u00ed, vyl\u00fa\u010denie in\u00fdch mo\u017en\u00fdch pr\u00ed\u010din \u0165a\u017ekost\u00ed, ale aj to, \u010di do\u010dasn\u00e9 obmedzenie histam\u00ednu v strave prinesie zlep\u0161enie. A\u017e v\u0161etky tieto inform\u00e1cie spolu pom\u00e1haj\u00fa pri spr\u00e1vnom pos\u00faden\u00ed probl\u00e9mu.<\/p>

Ako m\u00f4\u017ee SIBO prispieva\u0165 k probl\u00e9mom s histam\u00ednom?<\/strong><\/h2>

A teraz sa dost\u00e1vame sp\u00e4\u0165 k tomu, pre\u010do SIBO a probl\u00e9my s histam\u00ednom id\u00fa \u010dastokr\u00e1t ruka v ruke. Jedn\u00fdm z d\u00f4vodov je pr\u00e1ve \u010drevn\u00e1 sliznica. Ako sme u\u017e spom\u00ednali, nach\u00e1dza sa v nej enz\u00fdm DAO, ktor\u00fd pom\u00e1ha odb\u00farava\u0165 histam\u00edn prijat\u00fd potravou. Pri SIBO m\u00f4\u017ee doch\u00e1dza\u0165 k podr\u00e1\u017edeniu a naru\u0161eniu \u010drevnej sliznice. A ke\u010f sliznica nefunguje tak, ako by mala, m\u00f4\u017ee sa zhor\u0161i\u0165 aj schopnos\u0165 odb\u00farava\u0165 histam\u00edn.<\/p>

Do hry v\u0161ak vstupuj\u00fa aj samotn\u00e9 bakt\u00e9rie. Niektor\u00e9 z nich toti\u017e dok\u00e1\u017eu vytv\u00e1ra\u0165 histam\u00edn. Pri naru\u0161en\u00ed rovnov\u00e1hy \u010drevn\u00e9ho mikrobi\u00f3mu sa tak m\u00f4\u017ee meni\u0165 aj mno\u017estvo histam\u00ednu, ktor\u00e9 vznik\u00e1 priamo v na\u0161om \u010dreve.<\/p>

SIBO z\u00e1rove\u0148 nar\u00fa\u0161a prostredie \u010dreva a m\u00f4\u017ee ovplyv\u0148ova\u0165 aj \u010drevn\u00fa bari\u00e9ru. V \u010drevnej sliznici sa nach\u00e1dzaj\u00fa mastocyty \u2013 bunky imunitn\u00e9ho syst\u00e9mu, ktor\u00e9 sa podie\u013eaj\u00fa na obrann\u00fdch reakci\u00e1ch organizmu. Pri podr\u00e1\u017eden\u00ed \u010dreva sa v\u0161ak tieto bunky m\u00f4\u017eu aktivova\u0165 vo zv\u00fd\u0161enej miere a uvo\u013e\u0148ova\u0165 viac histam\u00ednu ne\u017e za be\u017en\u00fdch okolnost\u00ed. T\u00fdm sa jeho mno\u017estvo v organizme m\u00f4\u017ee e\u0161te viac zvy\u0161ova\u0165.<\/p>

V\u00fdsledkom m\u00f4\u017ee by\u0165, \u017ee sa v tele hromad\u00ed viac histam\u00ednu, ne\u017e ho telo dok\u00e1\u017ee odb\u00fara\u0165. A pr\u00e1ve to m\u00f4\u017ee by\u0165 jeden z d\u00f4vodov, pre\u010do sa pri SIBO objavuj\u00fa alebo zhor\u0161uj\u00fa aj probl\u00e9my s histam\u00ednom.<\/p>

Ke\u010f di\u00e9ta prinesie \u00fa\u013eavu, ale nerie\u0161i pr\u00ed\u010dinu<\/strong><\/h2>

Ak ste sa v niektor\u00fdch z uveden\u00fdch pr\u00edznakov na\u0161li, stoj\u00ed za to zamyslie\u0165 sa, \u010di za \u010das\u0165ou va\u0161ich probl\u00e9mov nestoj\u00ed aj histam\u00edn. Do\u010dasn\u00e9 vyradenie potrav\u00edn s vysok\u00fdm obsahom histam\u00ednu m\u00f4\u017ee prinies\u0165 v\u00fdrazn\u00fa \u00fa\u013eavu a pom\u00f4c\u0165 zmierni\u0165 nepr\u00edjemn\u00e9 pr\u00edznaky.<\/p>

Ale pozor. Rovnako ako low-FODMAP di\u00e9ta pri SIBO, aj n\u00edzkohistam\u00ednov\u00e1 di\u00e9ta pri histam\u00ednovej intolerancii m\u00e1 svoje obmedzenia. Na jednej strane si chceme pom\u00f4c\u0165, a preto dodr\u017eiavame di\u00e9tu, aby sme zmiernili nepr\u00edjemn\u00e9 pr\u00edznaky. Na druhej strane si v\u0161ak pr\u00edli\u0161n\u00fdm a dlhodob\u00fdm obmedzovan\u00edm stravy m\u00f4\u017eeme vytv\u00e1ra\u0165 \u010fal\u0161\u00ed probl\u00e9m.<\/p>

\u010c\u00edm viac potrav\u00edn vyra\u010fujeme, t\u00fdm chudobnej\u0161\u00ed a jednotv\u00e1rnej\u0161\u00ed m\u00f4\u017ee by\u0165 n\u00e1\u0161 jed\u00e1lni\u010dek. A t\u00fdm m\u00f4\u017eeme ochudob\u0148ova\u0165 aj n\u00e1\u0161 \u010drevn\u00fd mikrobi\u00f3m. Na jeho v\u00fdznam sa st\u00e1le \u010dasto zab\u00fada, pritom jeho zlo\u017eenie a rozmanitos\u0165 ovplyv\u0148uj\u00fa mno\u017estvo d\u00f4le\u017eit\u00fdch procesov v na\u0161om tele.<\/p>

A pr\u00e1ve tu sa m\u00f4\u017eeme dosta\u0165 do za\u010darovan\u00e9ho kruhu. Di\u00e9ta n\u00e1m m\u00f4\u017ee prinies\u0165 \u00fa\u013eavu a zmierni\u0165 nepr\u00edjemn\u00e9 pr\u00edznaky. Samotn\u00e9 pr\u00edznaky s\u00fa v\u0161ak \u010dasto iba sign\u00e1lom, \u017ee v na\u0161om tele nie\u010do nie je v poriadku. Histam\u00ednov\u00e1 intolerancia nie je samostatn\u00e9 ochorenie, ale sk\u00f4r d\u00f4sledok ur\u010ditej nerovnov\u00e1hy v organizme.<\/p>

Ak dostaneme diagn\u00f3zu histam\u00ednovej intolerancie, nemali by sme sa preto s\u00fastredi\u0165 iba na di\u00e9tu a zmier\u0148ovanie pr\u00edznakov. D\u00f4le\u017eit\u00e9 je h\u013eada\u0165 aj skuto\u010dn\u00fa pr\u00ed\u010dinu, pre\u010do na\u0161e telo histam\u00edn nedok\u00e1\u017ee dostato\u010dne odb\u00farava\u0165. T\u00e1 toti\u017e \u010dasto zost\u00e1va nepov\u0161imnut\u00e1 a nerie\u0161en\u00e1.<\/p>

Preto by sme ani pri SIBO, ani pri probl\u00e9moch s histam\u00ednom nemali zosta\u0165 iba pri potl\u00e1\u010dan\u00ed pr\u00edznakov pomocou di\u00e9ty. Di\u00e9ta m\u00f4\u017ee by\u0165 pomocnou barli\u010dkou, ktor\u00e1 n\u00e1m na ur\u010dit\u00fd \u010das u\u013eav\u00ed, ale z dlhodob\u00e9ho h\u013eadiska nie je rie\u0161en\u00edm st\u00e1le vyra\u010fova\u0165 z jed\u00e1lni\u010dka \u010fal\u0161ie a \u010fal\u0161ie potraviny, ktor\u00e9 netolerujeme. Pr\u00edli\u0161n\u00fdm obmedzovan\u00edm stravy si toti\u017e m\u00f4\u017eeme \u010dasom vytvori\u0165 \u010fal\u0161\u00ed probl\u00e9m.<\/p>

Ove\u013ea d\u00f4le\u017eitej\u0161ie je n\u00e1js\u0165 ten ch\u00fdbaj\u00faci k\u00fasok sklada\u010dky. Pochopi\u0165, \u010do sa v na\u0161om tele skuto\u010dne deje, pre\u010do sa v \u0148om histam\u00edn hromad\u00ed vo v\u00e4\u010d\u0161om mno\u017estve a \u010do tento probl\u00e9m st\u00e1le udr\u017eiava.<\/p>

Pr\u00e1ve h\u013eadanie a rie\u0161enie skuto\u010dnej pr\u00ed\u010diny n\u00e1m m\u00f4\u017ee pom\u00f4c\u0165 nielen dosta\u0165 sa z koloto\u010da neust\u00e1leho vyra\u010fovania \u010fal\u0161\u00edch potrav\u00edn, ale najm\u00e4 zmierni\u0165 na\u0161e \u0165a\u017ekosti, postupne obnovi\u0165 rovnov\u00e1hu v tele a op\u00e4\u0165 sa c\u00edti\u0165 lep\u0161ie.<\/p>

Odborn\u00e9 zdroje<\/h3>

  1. Comas-Bast\u00e9 O. et al. Histamine Intolerance: The Current State of the Art. Biomolecules. 2020;10(8):1181.<\/em><\/p><\/li>

  2. Reese I. et al. Guideline on management of suspected adverse reactions to ingested histamine. Allergo J Int. 2021;30:305\u2013314.<\/em><\/p><\/li>

  3. Hrubisko M. et al. Histamine Intolerance\u2014The More We Know the Less We Know. A Review. Nutrients. 2021;13(7):2228.<\/em><\/p><\/li>

  4. De Palma G. et al. Histamine-producing bacteria and their role in gastrointestinal disorders. Expert Rev Gastroenterol Hepatol. 2023.<\/em><\/p><\/li>

  5. Mou Z. et al. The taxonomic distribution of histamine-secreting bacteria in the human gut microbiome. BMC Genomics. 2021;22:695.<\/em><\/p><\/li>

  6. Riordan S.M. et al. Luminal bacteria and small-intestinal permeability. Scand J Gastroenterol. 1997;32(6):556\u2013563.<\/em><\/p><\/li>

  7. So D. et al. Effects of a low FODMAP diet on the colonic microbiome in irritable bowel syndrome: a systematic review with meta-analysis. Am J Clin Nutr. 2022.<\/em><\/p><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

    Histam\u00ednov\u00e1 intolerancia a SIBO: Ak\u00e1 je medzi nimi s\u00favislos\u0165? Tr\u00e1viace probl\u00e9my, ako s\u00fa nafukovanie, bolesti brucha, hna\u010dka, reflux \u010di nepr\u00edjemn\u00e9 […]<\/p>\n","protected":false},"author":2,"featured_media":7244,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"disabled","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"enabled","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7243","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nezaradene"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t